Science behind Baceteria, Viruses and Vaccines

Science behind Baceteria, Viruses and Vaccines

Humanity lives synergistically with pathogens (Bacteria and Viruses). They actually have a purpose.

MUMPS: Researchers investigated whether mumps might engender immunity to ovarian cancer through antibodies against the cancer-associated antigen MUC1 abnormally expressed in the inflamed parotid gland.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951028/

MEASLES: Albonico et al found that adults are significantly protected against non-breast cancers — genital, prostate, gastrointestinal, skin, lung, ear-nose-throat, and others — if they contracted measles (odds ratio, OR = 0.45), rubella (OR = 0.38) or chickenpox (OR = 0.62) earlier in life. [Med Hypotheses 1998; 51(4): 315-20].

https://www.ncbi.nlm.nih.gov/m/pubmed/9824838/

MEASLES: Montella et al found that contracting measles in childhood reduces the risk of developing lymphatic cancer in adulthood [Leuk Res 2006; 30(8): 917-22].

http://www.lrjournal.com/art…/S0145-2126(05)00466-2/abstract

https://www.ncbi.nlm.nih.gov/m/pubmed/16406019/

MEASLES: Alexander et al found that infection with measles during childhood is significantly protective — it cuts the risk in half — against developing Hodgkin’s disease (OR = 0.53) [Br J Cancer 2000; 82(5): 1117-21].

http://www.nature.com/bjc/journal/v82/n5/full/6691049a.html

https://www.ncbi.nlm.nih.gov/m/pubmed/10737396/

Measles to the Rescue: A Review of Oncolytic Measles Virus.
MV Clinical trials are producing encouraging preliminary results in ovarian cancer, myeloma and cutaneous non-Hodgkin lymphoma, and the outcome of currently open trials in glioblastoma multiforme, mesothelioma and squamous cell carcinoma are eagerly anticipated.
Aref S, et al. Viruses. 2016.

http://www.mdpi.com/1999-4915/8/10/294

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086626/

MEASLES: Glaser et al also found that lymph cancer is significantly more likely in adults who were not infected with measles, mumps or rubella in childhood [In J Cancer 2005; 115(4): 599-605].

http://onlinelibrary.wiley.com/doi/10.1002/ijc.20787/full

COMMON INFECTIONS: Gilham et al found that infants with the least exposure to common infections have the greatest risk of developing childhood leukemia [BMJ 2005; 330: 1294].

http://www.bmj.com/content/330/7503/1294

https://www.ncbi.nlm.nih.gov/m/pubmed/15849205/

EARLY EXPOSURE TO INFECTIONS:Urayama et al also found that early exposure to infections is protective against leukemia [Int J Cancer 2011; 128(7): 1632-43]. Read more….

http://onlinelibrary.wiley.com/doi/10.1002/ijc.25752/full

https://www.ncbi.nlm.nih.gov/m/pubmed/21280034/

CHICKEN POX (VARICELLA Canniff J., Donson A.M., Foreman N.K., Weinberg A. Cytotoxicity of glioblastoma cells mediated ex vivo by varicella-zoster virus-specific T cells. J Neurovirol. 2011;17(October (5)):448–454. [PubMed] Canniff et al. reported an association between those individuals with clinical or laboratory evidence of varicella-zoster virus (VZV) infection and lower risk of glioma.A glioma is a type of tumor that starts in the brain or spine. It is called a glioma because it arises from glial cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759842/…

CHICKEN POX IN CHILDHOOD: Silverberg J.I., Kleiman E., Silverberg N.B., Durkin H.G., Joks R., Smith-Norowitz T.A. Chickenpox in childhood is associated with decreased atopic disorders, IgE, allergic sensitization, and leukocyte subsets. Pediatr Allergy Immunol. 2012;23(February (1):50–58. [PubMed Silverberg et al. also reported that wild-type VZV infection up to 8 years of age was found to be protective against atopic disorders that are thought to be “mediated by suppression of IgE production and allergic sensitization, as well as altered leukocyte distributions. Chicken Pox references taken from Goldman, King STUDY

http://onlinelibrary.wiley.com/…/j.1399-3038.2011.0122…/full

https://www.ncbi.nlm.nih.gov/m/pubmed/22017482/

INFLUENZA – Influenza Virus Infection Elicits Protective Antibodies and T Cells Specific for Host Cell Antigens Also Expressed as Tumor-Associated Antigens: A New View of Cancer ImmunosurveillanceUzoma K. Iheagwara, Pamela L. Beatty, Phu T. Van, Ted M. Ross, Jonathan S. Minden, and Olivera J. Fin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006373/

THIS IS COOL!

Measles virus for cancer therapy
Stephen J. Russell, M.D., Ph.D. and Kah Whye Peng, Ph.D.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926122/

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